中国农业科学院兰州兽医研究所研究员、博士生导师，中国农业科学院“青年英才计划”入选者。自2009年以来，一直致力于负链RNA病毒的研究工作，以分子病毒学和结构生物学互为交叉，研究重点主要集中于病毒基因组结构与功能、病毒RNA合成、蛋白-蛋白相互作用、抗病毒药物和烈性外来传染病传播机制等基础研究，以及新型分子标记疫苗和活病毒载体疫苗研发等应用研究。近年来在 Journal of Virology、Molecular Therapy Oncolytics、PLoS Pathogens、Viruses、Frontiers in Microbiology 等国际期刊发表多篇文章，并担任 Virologica Sinica、Journal of Medical Virology、Frontiers in Microbiology、Frontiers in Immunology、Animal Health Research Reviews 等多个期刊杂志独立审稿人。

主持项目：

兰州兽医研究所“青年英才计划”配套经费，主持人，200万元

中国农业科学院“青年英才计划”人才项目，主持人，300万元

甘肃省自然科学基金面上项目，埃博拉病毒糖蛋白G介导病毒粒子侵入细胞分子机制的研究（2021-2023），主持人，6万元

中国农业科学院兰州兽医研究所，科研业务费项目（2021-2023年），主持人，30万元

•Weike Li, Ryan H. Gumpper, Yusuf Uddin, Ingeborg Schmidt-Krey, Ming Luo*, Complementary Mutations in the N and L Proteins for Restoration of Viral RNA Synthesis. Journal of Virology, 2018, 92(22): e01417-18. (IF: 4.324)

•Ryan H. Gumpper#, Weike Li#, Ming Luo*, Constraints of Viral RNA Synthesis on Codon Usage of Negative-StrandRNA Virus. Journal of Virology, 2019, 93(5): e01775-18.  (Co-First Author) (IF:4.324)

•Weike Li, Ravi Chakra Turaga,Xin Li, MalvikaSharma, Zahra Enadi,Sydney Nicole Dunham Tompkins, Kyle Christian Hardy, FalguniMishra, Jun Tsao, Zhi-renLiu, DapingFan, Ming Luo*, Overexpression of Smacby an armed vesicular stomatitis virus overcomes tumor resistance. Molecular Therapy Oncolytics, 2019, 14: 188–195. (IF: 5.71)

•Weike Li, Tiansong Li, Yuxiu Liu, Yuwei Gao, Songtao Yang, Na Feng, Heting Sun, Shengle Wang, Lei Wang, ZhigaoBu*, Xianzhu Xia*; Genetic characterization of an isolate of canine distempervirus from a Tibetan Mastiff in China, Virus Genes, 2014, 49:45-57.(IF:1.616)

•Yongfeng Li, Mengqi Yuan, Yuying Han, Libao Xie, Yuteng Ma, Su Li,Yuan Sun, Yuzi Luo, Weike Li*, Hua-Ji Qiu*. 2021. The UniqueGlycosylation at Position 986 on the E2 Glycoprotein of Classical Swine FeverVirus Is Responsible for Viral Attenuation and Protection against LethalChallenge. Journal of Virology, (IF: 5.103，共同通讯作者）

•Chen Guohua#, He Xiaobing#, Jia Huaijie, Fang Yongxiang, Wang Xiaoxia, Lou Zhongzi, Yang Fan, Li Weike*, Jing Zhizhong*. 2021.Identification and screening of host proteins interacting with ORFV-ORF047protein. Virology Journal 18:27.(IF: 4.099, 共同通讯作者)

• Fan Yang, Jinlong Tan,Yongxiang Fang, Guohua Chen, Yongzhi Zhang,Qianqian Hu, Wuweiyi Han, Yongsheng Liu, Baoquan Fu, Zhizhong Jing, Weike Li*. 2022. The multiplicity of Infection ofRecombinant Vaccinia Virus Expressing the T7 RNA Polymerase Determines theRescue Efficiency of Vesicular Stomatitis Virus. Frontiers in Microbiology. (IF: 6.064)

•Xie Libao, Han Yuying, Ma Yuteng, Yuan Mengqi, Li Weike, Li Lian-Feng, Li Miao, Sun Yuan, Luo Yuzi, Li Su, Hu Shouping, Li Yongfeng*, QiuHua-Ji*.2020.P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation ofClassical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. Journal of Virology 94.(IF: 5.103)

•Ryan H. Gumpper, Weike Li, Carlos H. Castañeda, M. José Scuderi, James K. Bashkin, Ming Luo*, A Polyamide Inhibits Replication of Vesicular Stomatitis Virus byTargeting RNA in the Nucleocapsid. Journal of Virology, 2018, 92(8): e00146-18. (IF: 4.324)

•Zhu Si, Jiayan Zhang, Sakar Shivakoti, Ivo Atanasov, Chang-Lu Tao, Wong H. Hui, Kang Zhou, Xuekui Yu, Weike Li, Ming Luo, Guo-Qiang Bi, Z. Hong Zhou*, Different functional states of fusion protein gBrevealed on human cytomegalovirus by cryoelectron tomography with Volta phase plate. PLoS Pathogens, 2018, 14(12): e1007452. (IF: 6.463)

•Yongfeng Li, Lian-Feng Li, Shaoxiong Yu, Xiao Wang, Lingkai Zhang, Jiahui Yu, Libao Xie, Weike Li, RazimAli, Hua-Ji Qiu*, Applications of Replicating-Competent Reporter-Expressing Viruses in Diagnosticand Molecular Virology. Viruses, 2016, 8(5): 127. (IF: 3.811)

•Jinlong Tan, Yinju Liu, Fan Yang, Guohua Chen, Yongxiang Fang, Xiaobing He, Zhongzi Lou, Huaijie Jia, Zhizhong Jing*, Weike Li *，Emerging evidence for poxvirus-mediated unfolded protein response: Lumpy skin disease virus maintains self-replication by activating PERK and IRE1 signaling. The FASEB Journal，2023,37(5):e22902.

专利和标准：

1. 景志忠，张莉敏，朱武，房永祥，陈国华，张亚娟，何小兵，景伟，李维克，贾怀杰，娄忠子，高建平，张春祥，付宝权。甘肃省地方标准“牛结节性皮肤病防控技术规范”DB62/T 4633-2022。
2. 景志忠，高建平，唐豪，陈国华，张勇，房永祥，何小兵，景伟，李维克，贾怀杰，娄忠子，张春祥，付宝权。甘肃省地方标准“牛结节性皮肤病血清学诊断技术” DB62/T 4634-2022。