2009.09-2013.07 内蒙古科技大学,生命科学与技术学院,生物技术,理学学士。
2013.09-2016.07 温州医科大学,眼视光学院、生物医学工程学院,生物学,理学硕士。
2016.10-2017.09 北京理工大学,生命学院,研究助理。
2017.09-2018.10 北京理工大学,生命学院,化学工程与技术,博士在读。
2018.10-2019.08 中国农业科学院上海兽医研究所,研究助理。
2019.09-2022.06 中国农业科学院研究生院,兽药学, 农学博士。
2022.09 -至今 外围买球十大平台,萃英博士后。
主要从事(1)基因编辑工具开发与优化;(2)利用基因编辑进行高通量筛选:病毒与宿主互作及抗病毒药物研发。以第一作者和共同第一作者在The CRISPR Journal、Molecular Therapy-Nucleic Acids等杂志发表SCI论文5篇,以参与者在PLoS Biology、Molecular Therapy、ACS Applied Materials & Interfaces、Journal of Biological Chemistry等杂志发表SCI论文12篇。
1. Fayu Yang, et al. Green Fluorescent Protein Tagged Polycistronic Reporter System Reveals Functional Editing Characteristics of CRISPR-Cas. The CRISPR Journal. 2022. DOI: 10.1089/crispr.2021.0056.
2. Fayu Yang, et al. Genome Editing of Corynebacterium glutamicum Mediated with Cpf1 Plus Ku/LigD. Biotechnology Letters. 2021, 43(12):1-9.
3. Fayu Yang, et al. Functional Non-homologous End Joining Pattern Triggered by CRISPR/Cas9 in Human Cells. Journal of Genetics and Genomics. 2018, 45(6):329-332.
4. Fayu Yang, et al. CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool. Molecular Therapy-Nucleic Acids. 2017, 7: 378–386.
5. Fayu Yang, et al. Local Polyploidy Phenomenon in Escherichia coli and its Significance in Genetic Engineering. BioRxiv. 2018. doi: https://doi.org/10.1101/335448.
6. Fengtao Dang#, Fayu Yang#, et al. A Novel Mutation, p.F32I, in GJA8 (Cx50) Causes Human Dominant Congenital Cataracts. International Journal of Ophthalmology. 2016, 9 (11), 1561.
7. Haihua Xie, Xianglian Ge, Fayu Yang, et al. High-fidelity SaCas9 Identified by Directional Screening in Human Cells. PLoS Biology. 2020, 18(7):e3000747.
8. Huihui Sun, Fanfan Li, Jie Liu, Fayu Yang, et al. A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing. Molecular Therapy. 2018, 26(8):2070-2076.
9. Xiubin He, Yufei Wang, Fayu Yang, et al. Boosting Activity of High-fidelity CRISPR/Cas9 Variants Using a tRNAGln-processing System in Human Cells. Journal of Biological Chemistry. 2019, 294, 9308-9315.
10. Jiao Zhang, Fayu Yang, et al. Optimizing a CRISPR-Cpf1-based Genome Eengineering System for Corynebacterium glutamicum. Microbial Cell Factories. 2019, 18, 60.
11. Lu Shang, Yuting Wu, Nan Wei, Fayu Yang, et al. Novel Arginine End-Tagging Antimicrobial Peptides to Combat Multidrug-Resistant Bacteria. ACS Applied Materials & Interfaces. 2022, 14 (1): 245–258.
12. Guohui Chuai, Fayu Yang, et al. Deciphering Relationship Between Microhomology and In-frame Mutation Occurrence in Human CRISPR-based Gene Knockout. Molecular Therapy -Nucleic Acids. 2016, 5, e323.